[Comparison of seasonal influenza vaccines: composition and properties].
Identifieur interne : 000270 ( Main/Exploration ); précédent : 000269; suivant : 000271[Comparison of seasonal influenza vaccines: composition and properties].
Auteurs : R. Allwinn [Allemagne] ; H W DoerrSource :
- Deutsche medizinische Wochenschrift (1946) [ 1439-4413 ] ; 2011.
Descripteurs français
- KwdFr :
- Adjuvants immunologiques (administration et posologie), Adolescent, Adulte, Adulte d'âge moyen, Allemagne, Complexes immunostimulants (), Complexes immunostimulants (effets indésirables), Complexes immunostimulants (immunologie), Culture virale (), Enfant, Enfant d'âge préscolaire, Grippe humaine (), Grippe humaine (immunologie), Humains, Jeune adulte, Liposomes, Nourrisson, Sujet âgé, Vaccination de masse, Vaccins antigrippaux (), Vaccins antigrippaux (effets indésirables), Vaccins antigrippaux (immunologie), Vaccins inactivés (), Vaccins inactivés (effets indésirables), Vaccins inactivés (immunologie), Vaccins sous-unitaires (), Vaccins sous-unitaires (effets indésirables), Vaccins sous-unitaires (immunologie), Vaccins à ADN (), Vaccins à ADN (effets indésirables), Vaccins à ADN (immunologie), Vaccins à virosomes (), Vaccins à virosomes (effets indésirables), Vaccins à virosomes (immunologie), Virus de la grippe A (immunologie).
- MESH :
- administration et posologie : Adjuvants immunologiques.
- effets indésirables : Complexes immunostimulants, Vaccins antigrippaux, Vaccins inactivés, Vaccins sous-unitaires, Vaccins à ADN, Vaccins à virosomes.
- immunologie : Complexes immunostimulants, Grippe humaine, Vaccins antigrippaux, Vaccins inactivés, Vaccins sous-unitaires, Vaccins à ADN, Vaccins à virosomes, Virus de la grippe A.
- Adolescent, Adulte, Adulte d'âge moyen, Allemagne, Complexes immunostimulants, Culture virale, Enfant, Enfant d'âge préscolaire, Grippe humaine, Humains, Jeune adulte, Liposomes, Nourrisson, Sujet âgé, Vaccination de masse, Vaccins antigrippaux, Vaccins inactivés, Vaccins sous-unitaires, Vaccins à ADN, Vaccins à virosomes.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Adjuvants, Immunologic (administration & dosage), Adolescent, Adult, Aged, Child, Child, Preschool, Germany, Humans, ISCOMs (adverse effects), ISCOMs (chemistry), ISCOMs (immunology), Infant, Influenza A virus (immunology), Influenza Vaccines (adverse effects), Influenza Vaccines (chemistry), Influenza Vaccines (immunology), Influenza, Human (immunology), Influenza, Human (prevention & control), Liposomes, Mass Vaccination, Middle Aged, Vaccines, DNA (adverse effects), Vaccines, DNA (chemistry), Vaccines, DNA (immunology), Vaccines, Inactivated (adverse effects), Vaccines, Inactivated (chemistry), Vaccines, Inactivated (immunology), Vaccines, Subunit (adverse effects), Vaccines, Subunit (chemistry), Vaccines, Subunit (immunology), Vaccines, Virosome (adverse effects), Vaccines, Virosome (chemistry), Vaccines, Virosome (immunology), Virus Cultivation (methods), Young Adult.
- MESH :
- chemical , administration & dosage : Adjuvants, Immunologic.
- chemical , adverse effects : ISCOMs, Influenza Vaccines, Vaccines, DNA, Vaccines, Inactivated, Vaccines, Subunit, Vaccines, Virosome.
- chemical , chemistry : ISCOMs, Influenza Vaccines, Vaccines, DNA, Vaccines, Inactivated, Vaccines, Subunit, Vaccines, Virosome.
- chemical , immunology : ISCOMs, Influenza Vaccines, Vaccines, DNA, Vaccines, Inactivated, Vaccines, Subunit, Vaccines, Virosome.
- geographic : Germany, Liposomes.
- immunology : Influenza A virus, Influenza, Human.
- methods : Virus Cultivation.
- prevention & control : Influenza, Human.
- Adolescent, Adult, Aged, Child, Child, Preschool, Humans, Infant, Mass Vaccination, Middle Aged, Young Adult.
Abstract
The influenza virus isolation in embryonated chicken eggs was possible early in 1930er years and allowed the influenza vaccine production. Most influenza vaccines were derived from this, but actually new virus cell culture methods are established. For better tolerability, influenza vaccines include only antigen proportions (split- and subunit vaccines) but with the disadvantage of minor vaccine efficacy. This was compared with the addition of adjuvants. Aluminium salts are used for many decades and still in use to enhance the effect of vaccines. New formulations are MF59, AS03, AS04 or toll- like receptor-agonists. Also virosomal formulations and "ISCOMs"(Immune Stimulating Complexes) are newly designed and compromises enhanced immune reactions. Actually a broad range of various influenza vaccines exist and are available for a very different group of patients (which depends on physical conditions, age, immune status or allergies).
DOI: 10.1055/s-0031-1292046
PubMed: 22048938
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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()</term><term>Vaccins à virosomes (effets indésirables)</term><term>Vaccins à virosomes (immunologie)</term><term>Virus de la grippe A (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Adjuvants, Immunologic</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>ISCOMs</term><term>Influenza Vaccines</term><term>Vaccines, DNA</term><term>Vaccines, Inactivated</term><term>Vaccines, Subunit</term><term>Vaccines, Virosome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>ISCOMs</term><term>Influenza Vaccines</term><term>Vaccines, DNA</term><term>Vaccines, Inactivated</term><term>Vaccines, Subunit</term><term>Vaccines, Virosome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>ISCOMs</term><term>Influenza Vaccines</term><term>Vaccines, DNA</term><term>Vaccines, 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Most influenza vaccines were derived from this, but actually new virus cell culture methods are established. For better tolerability, influenza vaccines include only antigen proportions (split- and subunit vaccines) but with the disadvantage of minor vaccine efficacy. This was compared with the addition of adjuvants. Aluminium salts are used for many decades and still in use to enhance the effect of vaccines. New formulations are MF59, AS03, AS04 or toll- like receptor-agonists. Also virosomal formulations and "ISCOMs"(Immune Stimulating Complexes) are newly designed and compromises enhanced immune reactions. Actually a broad range of various influenza vaccines exist and are available for a very different group of patients (which depends on physical conditions, age, immune status or allergies).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22048938</PMID><DateCompleted><Year>2011</Year><Month>12</Month><Day>19</Day></DateCompleted><DateRevised><Year>2011</Year><Month>11</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1439-4413</ISSN><JournalIssue CitedMedium="Internet"><Volume>136</Volume><Issue>45</Issue><PubDate><Year>2011</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Deutsche medizinische Wochenschrift (1946)</Title><ISOAbbreviation>Dtsch. Med. Wochenschr.</ISOAbbreviation></Journal><ArticleTitle>[Comparison of seasonal influenza vaccines: composition and properties].</ArticleTitle><Pagination><MedlinePgn>2315-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1055/s-0031-1292046</ELocationID><Abstract><AbstractText>The influenza virus isolation in embryonated chicken eggs was possible early in 1930er years and allowed the influenza vaccine production. Most influenza vaccines were derived from this, but actually new virus cell culture methods are established. For better tolerability, influenza vaccines include only antigen proportions (split- and subunit vaccines) but with the disadvantage of minor vaccine efficacy. This was compared with the addition of adjuvants. Aluminium salts are used for many decades and still in use to enhance the effect of vaccines. New formulations are MF59, AS03, AS04 or toll- like receptor-agonists. Also virosomal formulations and "ISCOMs"(Immune Stimulating Complexes) are newly designed and compromises enhanced immune reactions. Actually a broad range of various influenza vaccines exist and are available for a very different group of patients (which depends on physical conditions, age, immune status or allergies).</AbstractText><CopyrightInformation>© Georg Thieme Verlag KG Stuttgart · New York.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Allwinn</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institut für Med. Virologie und Impfambulanz, Frankfurt/Main. allwinn@em.uni-frankfurt.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Doerr</LastName><ForeName>H W</ForeName><Initials>HW</Initials></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><VernacularTitle>Saisonale Influenza-Impfstoffe: Zusammensetzung und Eigenschaften.</VernacularTitle><ArticleDate DateType="Electronic"><Year>2011</Year><Month>11</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Dtsch Med 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Subunit</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D022721">Vaccines, Virosome</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000276" MajorTopicYN="N">Adjuvants, Immunologic</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016882" MajorTopicYN="N">ISCOMs</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008081" MajorTopicYN="N">Liposomes</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D032541" MajorTopicYN="N">Mass Vaccination</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019444" MajorTopicYN="N">Vaccines, DNA</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015164" MajorTopicYN="N">Vaccines, Inactivated</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D022223" MajorTopicYN="N">Vaccines, Subunit</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D022721" MajorTopicYN="N">Vaccines, Virosome</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014776" MajorTopicYN="N">Virus Cultivation</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>11</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>11</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2011</Year><Month>12</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">22048938</ArticleId><ArticleId IdType="doi">10.1055/s-0031-1292046</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country><region><li>District de Darmstadt</li><li>Hesse (Land)</li></region><settlement><li>Francfort-sur-le-Main</li></settlement></list><tree><noCountry><name sortKey="Doerr, H W" sort="Doerr, H W" uniqKey="Doerr H" first="H W" last="Doerr">H W Doerr</name></noCountry><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Allwinn, R" sort="Allwinn, R" uniqKey="Allwinn R" first="R" last="Allwinn">R. 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